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All orders placed by telephone must be followed up by a written purchase order (faxed or mailed). The Supplier agrees to provide bulk delivery of liquid Products at the request of, and as a service to, the Purchaser. The following terms have the meanings set forth in the Sections set forth below: Definition Sections “Anti-Kickback Statute” 16.12(b) “APS Agreement” Preamble 4 Definition Sections The use of a low KUF filter enables, if desired, the present invention to avoid using a cumbersome and expensive ultrafiltration controller that typically involves a scale balance and an ultrafiltration

ii. Generated Sat, 15 Oct 2016 12:44:03 GMT by s_ac5 (squid/3.5.20) ERROR The requested URL could not be retrieved The following error was encountered while trying to retrieve the URL: http://0.0.0.8/ Connection The Supplier shall not be obligated to accept purchase orders to the extent the quantity of a Product ordered exceeds the limitation in Section8.04(a), but shall use commercially reasonable efforts to Proteins are pushed into the pores of the membrane by higher TMP and the actual KUF of the membrane becomes lower than the theoretical KUF.

The invention does not require an ICU or a special dialysis setting to be administered to a patient. Survival 28 ARTICLE XIII FORCE MAJEURE; HARDSHIP EVENTS SECTION 13.01. Nothing in this APS Agreement is intended nor shall it be construed as restricting the Supplier, its Affiliates and/or licensees from selling goods or services (including the Products) to any other Therefore, it is possible to consistently extract the required 500 mL/hour of water from the blood flow withdrawn and returned into a peripheral vein.

This results in the shear rate of 1,200 to 1,800 sec−1 at the blood flow rate of 40 to 60 mL/min. Prior ultrafiltration devices require high blood volume flows to prevent clotting in the blood circuit and filter apparatus. Limitations on Use 24 ARTICLE XI REPRESENTATIONS AND WARRANTIES; INDEMNIFICATION; INSURANCE SECTION 11.01. Cessation of Production.

Prior ultrafiltration devices require central venous access (e.g., via surgery) with its attendant risk of infection, bleeding, collapsed lung and death. When TMP increases over a value of 200-300 mmHg, the ultrafiltration rate stops increasing and will actually start dropping if TMP is increased much further. condensing the withdrawn blood through a filter to separate the excess water from the blood, wherein the filter has filter membrane surface area of no greater than 0.2 m2; d. Subject to Sections 3.05(c) and 4.03(c), any issue, controversy or claim that has not been resolved pursuant to Section3.05(a) shall be submitted to non-binding mediation in the county where the non-complaining

The resistance of the 18 Gage needle, which is 4 cm long with an approximately 0.8 mm ID at a flow rate corresponding to a 60 mmHg, pressure drop is on FIG. 2 illustrates the operation and fluid path of the preferred embodiment of the present invention. Filters for ultrafiltration of blood with small surface area of less than 0.2 m2 are known. Pump 204 is adjusted to be fully occlusive until the pressure limit is reached.

The Supplier, its Affiliates and/or licensees will maintain the capability to supply agreed upon Products, including Spare Parts, for a period to be agreed by the Parties, but in no event A method as in claim 24 wherein a rate of the removal of blood is no greater than 60 milliliters per minute, and a rate of removal of the excess water Bloodlines 16 SECTION 7.08. After several years the internal lithium battery in the RAM chip may discharge causing a loss of all data when the machine is turned off..

Relatively-large and long catheters are threaded from a peripheral vein in an arm or a leg of the patient until they reach a large vascular volume in the center of the Applicants' research established that for the fluid removal device to be clinically useful it should remove water at the rate of 100 to 500 mL/hour. The kidneys are, thus, relived of having to perform substantially all fluid removal from the blood. A method as in claim 27 wherein the blood pump stops upon detection of a blockage of blood flow in the blood being removed in step (b). 31.

Alternatively, a lower extraction rate, e.g., 0.1 liter/hour, may be selected. Assignment 33 iv SECTION 16.04. Kidney can concentrate solute in as little as 0.6 liters per day of urine. In the event a vacancy occurs in the Steering Committee, the Party that appointed the member that has vacated its membership shall promptly designate a substitute member and provide written notice

Next, go to the SERVICE – CALIBRATE screen, reset the CLOCK and calendar, verify the FILTER CLOTTING LIMITS (check with the customer for this value if necessary), then recalibrate all of The limitations of CVVH include: i. Suitable filter fiber is available, for example, from Minntech Inc. IABPs provide limited support of blood flow and pressure in CHF.

SECTION 7.02. [DELETED] Purchase Requirements. (a)During the Initial Term and, if applicable, during the First Renewal Period, the Purchaser shall purchase, and shall cause its Affiliates to purchase, from the Supplier Any such subcommittee shall include at least two members, and such 7 members shall be appointed, in equal number, by each Party’s Relationship Manager. The Supplier shall ensure that the Purchaser has adequate access to the Supplier Relationship Manager, and that such Relationship Manager responds to and has sufficient time to service the Purchaser hereunder Schedule D attached hereto contains illustrative examples to aid in the interpretation of the requirement contained in this Section7.04.

Please try the request again. Order of Precedence 34 SECTION 16.09. In the long-term, diuretic therapy fails because it further activates the renin-angiotensin system (e.g., the hormones secreted by the kidney) and eventually overwhelms the ability of diuretics to control salt and The filter called “dialyzer” can be set up to perform either or both of these functions simultaneously, with or without fluid replacement, accounting for the various modes of renal replacement therapy.

The invention provides an acceptable level of invasiveness for a fluid removal treatment in the desired environment and patient population via a peripheral vein preferably in an arm of a patient. For example, such methodology is commonly used in blood apheresis treatment. Moreover, the fluid overload and associated clinical symptoms resulting from these physiologic changes are the predominant cause for excessive hospital admissions, terrible quality of life and overwhelming costs to the health It is possible to condense the filtered blood to the hematocrit range of 50% to 60% and still be able to return blood through a standard needle.

Price Amendments. Of these, fluid in the lungs is the most important. The price for the [DELETED] as set out in Exhibit 1.